Choose your report
Choose Focus for one question or Complete for the wider picture.
One clear choice
When family history makes it personal
A condition runs in your family. Know what to ask at your next health check.
Private intakeNo public raw DNA upload.
Evidence frameworkPhD-led and evidence-weighted.
Context-awareYou, not just your genes.
Spoke reviews one compatible raw DNA file alongside your health and family history, prioritises evidence-backed areas worth discussing, and creates focused questions with a concise clinician summary. One-person report. Not a diagnosis.
1Choose your reportChoose Focus for one question or Complete for the wider picture.
2Buy securelyComplete payment without finding or uploading your DNA file first.
3Upload when readyUse the secure portal when your file is ready. Compatibility is confirmed before analysis.
Upload when readyChoose and pay without finding your raw DNA file first.
Checked before analysisThe exact uploaded file must pass format and coverage checks.
4 business daysUsual readiness after secure intake and file checks.
Consent-ledAnalysis only after explicit intake consent
Evidence-weightedFindings are separated by strength and usefulness
Portal deliveryNo report attachments in ordinary email
Deletion supportedRaw file retention is made explicit before upload
NIH · genomics literacyCDC · family historyACMG · secondary findings
Trust firstDesigned for careful decisions, not casual curiosity.
Compatibility firstNo raw file is collected on the public page.
Non-diagnostic by designReports support prevention review, not treatment decisions.
Deletion supportedDNA data handling is explicit before upload.
Your guided path
A calm, guided path from raw data to clarity.
We make sense of your DNA with care and clinical judgement, so you can focus on what matters most: living well, for you.
Boundary-aware interpretation
Private portal workflow
Concierge support every step
Buy securely
Complete payment without finding or uploading your DNA file first.
File not needed yetUpload when ready
Use the secure portal when your file is ready. Compatibility is confirmed before analysis.
Authoritative file checkOptional compatibility check
Already have your file to hand?
You can run a quick browser-only check for reassurance. It is not required to choose or buy a report, and the file is not retained.
Supported first23andMe, Ancestry, MyHeritage, and compatible raw-data exports.
Team review when neededWhole-genome VCF and unusual formats can be reviewed before purchase if you want certainty.
Boundaries up frontWe do not diagnose disease or tell you to start, stop, or change medication.
Your privacy is our priorityWe only collect what is needed to check fit. Your raw data is never collected on this page.
Check locally if you want
A small local sample checks file shape and likely compatibility. The file is not retained.
Return to report choice
Likely-compatible files continue normally. Unusual formats can be routed to manual review.
Sample report structure
See the report before you pay.
The report is designed to be read by a person who wants clarity, not another table of variants. Each section states what is known, what is uncertain, and what context would change the interpretation.
Page 1Summary
Priority findings
A short ranked view of the signals most likely to matter for the buyer's stated goal and family-history context.
Page 2Evidence
Confidence and caveats
Findings are separated into established, context-dependent, and exploratory groups so weak signals do not look stronger than they are.
Page 3Action
Questions for review
The output is a bounded set of follow-up questions for self-review or a clinician conversation, not a diagnosis checklist.
What you receive
A report built for decisions, not curiosity loops.
Spoke DNA Reports are useful when a genetic signal needs context. The report starts with what is most actionable, then shows uncertainty and evidence level before any suggested follow-up.
Prioritized signals
Relevant DNA signals considered alongside the family history you choose to share, without assuming a shared cause.
Limitations stated
Evidence strength, missing context, and clinical-confirmation boundaries kept visible.
Action map
Focused questions and useful measurements to discuss at your next health check.
Compatibility
Compatibility confirmed before analysis.
DNA providers differ by file version and marker coverage. The optional browser check can offer early reassurance; the exact secure upload makes the final decision before analysis starts.
File sourceStatusNotes
23andMe raw dataReadyText export. Older chip versions may have missing markers.
AncestryDNA raw dataReadyText export. Coverage varies by version and ancestry context.
MyHeritage raw dataReadyCSV or text export. Reviewed for marker coverage before analysis.
Whole-genome VCFManual reviewPotentially useful, but file size and annotation needs vary.
No DNA file yetNot eligibleSpoke currently interprets an existing compatible raw DNA file rather than arranging testing.
Method
Context changes what the DNA should mean.
A raw file can contain many signals. A professional report needs to decide which ones are useful for this person, this goal, and this level of evidence.
File and source check
After secure upload, we confirm whether the exact raw file is compatible before analysis can start.
Context intake
Your goals, family history, current screening status, and optional labs change which findings deserve attention.
Evidence review
Findings are grouped by confidence and usefulness, with uncertain signals kept visibly separate.
Action map
The report ends with bounded next questions, not diagnosis language or medication instructions.
Pricing
Simple pricing for personalized reports.
Choose one focused health question or a complete report across health areas.
A short ranked action map for one health question, with a full evidence appendix and concise clinician brief.
Choose a Focus areaA ranked action map across supported health areas, with a full evidence appendix and concise clinician brief.
Choose CompleteSecure intakeEncrypted storage
Quality controlsFramework maintained by Spoke Bio
Tailored guidanceClear next steps, always
Privacy and care
Your genetic data should be handled with care.
Our intake is deliberately guided, not a data grab. We keep payment intent separate from file upload, request consent before analysis, and support deletion requests.
Consent-first
Secure portal
Deletion supported
No raw DNA file leaves your browserThe public fit check reads a small local sample and does not retain the file.
Consent before analysisActual uploads happen through the secure portal flow.
No casual reuseData handling is limited to report delivery unless separate consent says otherwise.
Deletion requests supportedRetention and deletion are made explicit before upload.
Decision support
Read the evidence before choosing the service.
Best when a condition in your family has made your own health questions feel more immediate. These guides explain fit, scope, and responsible limits.
ScopeWhat can a raw DNA health report tell me?See what responsible interpretation may help with—and what it cannot claim.23andMeCan I use 23andMe raw data?Understand file fit, limitations, and clinical-confirmation boundaries.MethodHow Spoke reviews evidenceSee how findings are prioritised and uncertainty stays visible.
FAQ
Answer the trust questions before checkout.
Can this diagnose a condition?
No. The report is prevention and discussion support. It does not diagnose disease, order tests, or tell you to change medication.
Do I upload my DNA file in the public fit check?
No. The public fit check reads a small sample locally in your browser and does not retain the file. Secure upload happens later through the portal after consent.
What if my file is unsupported?
If the optional browser check flags the file, you can request review before purchase. If the exact secure upload cannot be used, we will help with a compatible export or refund you in full.
Will the report recommend supplements?
No supplement stack is generated. Where a genetic signal suggests a useful health question, the report keeps it framed as context for review.
Choose your report
Buy securely, then upload when ready.
You do not need the file to hand today. The exact file is checked after secure upload and cannot enter analysis until it passes.