Can I use 23andMe raw data for a health report?

Already have your raw DNA file?

Try the free browser file check to check its header, format, and a marker sample on your device. Your genome is not uploaded or retained. The result does not confirm full marker coverage or analyse your health; the exact file still needs compatibility checks after secure upload.

This check is optional. If you still need your file, follow the raw DNA download steps. You can choose a report before retrieving it.

Download the data, not a screenshot of your results

Use the original raw-data download from your 23andMe account. A screenshot, ancestry summary or list copied into a spreadsheet is not a substitute for the raw file. Keep the download unedited and store it privately while you decide where to use it.

What 23andMe raw data can support

A 23andMe raw-data file can contain enough markers to review selected health-related genetic signals, polygenic tendencies, medication-response context, and carrier-style markers when the evidence and coverage are appropriate.

Useful prevention questions, such as what may be worth checking or discussing.
Context-aware interpretation when family history, labs, medications, and screening status are considered.
A clear split between actionable findings, background context, and signals that should not drive decisions alone.

What it cannot responsibly do

Raw consumer DNA data is not the same as diagnostic sequencing. It can have missing markers, strand/build issues, chip-version gaps, and false positives. Important medical decisions should rely on clinical confirmation where appropriate.

How Spoke checks file fit

You can choose and buy a report before finding the file. After secure upload, Spoke checks the exact file before analysis can start. If you already have the file, the optional browser check can look at its source, shape, and a marker sample without retaining it.

Useful boundaries.

Do I need to upload my 23andMe file on the public page?

No. The public fit check does not store your genome file. Secure upload happens later through the portal after consent.

Can this replace clinical genetic testing?

No. It can help organize prevention questions, but it does not replace diagnostic testing, clinician review, or medication advice.

Scope, sources and supporting material

This guide can help with

When a 23andMe raw-data export may support careful health interpretation.
Why file fit and clinical confirmation boundaries matter.

This guide cannot answer

Whether a specific marker is medically diagnostic.
Whether your individual file is compatible without checking it.

Primary sources

Direct-to-consumer tests, US Food and Drug Administration
Direct-to-consumer genetic testing FAQ, National Human Genome Research Institute
Accessing your raw genetic data, 23andMe

Original Spoke artifact

Anonymised sample report

A three-gate checklist for deciding whether a 23andMe file can support responsible interpretation.

File gate: use the original downloaded raw-data export.
Coverage gate: check that the file contains enough relevant markers for the intended report.
Clinical gate: confirm findings that could affect screening, treatment, medication, or family planning.