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Spoke DNA Reports by Spoke Bio
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Early customer price · first 50 reports

Turn your raw DNA into a clearer health picture.

Spoke DNA helps turn your existing DNA file into a practical plan: what may be worth checking, what could wait, and where a clinician conversation might help.

Turn your existing 23andMe, AncestryDNA, MyHeritage, or Living DNA file into clearer priorities, evidence labels, and a concise summary you can use with your doctor or pharmacist.

Check file compatibility→ See sample report Ways to get your raw DNA file
A woman speaking with her doctor about a Spoke DNA report Sample report ↗Genome Action Plan · 245 report rows · 13 areas
Raw DNA accepted23andMe · AncestryDNA · MyHeritage · Living DNA
Private and deletableEncrypted upload · no sale · raw-file deletion controls
Doctor-ready summaryDoctor/pharmacist notes when a finding is worth discussing
Sample report firstSee the format before payment or upload

Educational, evidence-reviewed reports. Not diagnosis, treatment advice, or a replacement for clinical testing.

Start focused, or get the full Genome Action Plan.

Choose Focus if you have one clear question, or Complete if you want the full picture across your genome, context, and priorities.

Single health area

Focus

Best for one health area.

Early customer price · first 50 reports $140 Normally $200 one-time · creditable toward Complete for 30 days · usually ready within 4 business days after checks
  • A targeted answer for one area, such as sleep & fitness, heart & metabolic health, gut response, or medication safety
  • Your DNA, labs, and context pulled into one clear view
  • Practical next steps and checks worth considering now
  • A short doctor-ready summary for that specific question
Start with Focus See sample Focus report →
Recommended · most people

Full Genome Action Plan

Complete

Best balance of depth and price.

Early customer price · first 50 reports $330 Normally $470 one-time · complete report and doctor-ready summary · usually ready within 4 business days after checks
  • Your full Genome Action Plan across key health areas
  • The most useful findings prioritized first
  • Habits, routine checks, and doctor follow-ups clearly separated
  • Detailed appendices for traits, markers, medication response, and context
Choose Complete See sample Complete report →

Inside a Spoke report

A report built to reduce noise, not add more.

Many DNA reports stop at surfacing associations. Spoke is built to do the harder work after detection: quality-checking, ranking, and prioritising findings by evidence strength, trait importance, personal context, and whether they can responsibly support a next step.

  • Five practical next steps, on page one. No scrolling for the action. Lipid panel, glucose, vitamin D — measured tests named by name.
  • Built to avoid overreaction. Clear boundaries separate useful follow-up from findings that should not change care on their own.
  • Shareable clinical summary at the end. Plain enough for you to use; structured enough to share with your doctor if a finding needs follow-up.
Open the sample report→ Start your own report →

See what gets checked, tracked, discussed, and ignored for now.

Genome Action Plan
Opening overview from an anonymised Spoke DNA Genome Action Plan report
Worth your attention findings from an anonymised Spoke DNA Genome Action Plan report
Expanded 14-day plan options from an anonymised Spoke DNA Genome Action Plan report
Personal genome explorer from an anonymised Spoke DNA Genome Action Plan report
13 areas
5 steps
4 views

Method

How Spoke decides what matters.

Raw DNA can surface thousands of associations. Spoke finds what matters based on evidence strength, trait importance, personal context, and whether the result can responsibly support a next step.

Imputation QC

We check file quality and confidence before using a genetic signal.

LD-aware scoring

Scores account for nearby variants travelling together, not just isolated SNPs.

Evidence mapping

Findings are linked to literature, biomarkers, possible checks, and safety boundaries.

Prioritisation layer

Signals are ranked by relevance, actionability, and what should stay in the background.

FAQ

Privacy, upload, diagnosis, turnaround, and what the report can and cannot do.

What to know before checkout or upload.

Will this tell me if I'll get cancer or Alzheimer's?

No. Spoke does not predict whether you will get cancer, Alzheimer's, or any other condition. Sensitive areas such as cancer context, Alzheimer's, Parkinson's, and psychiatric traits are opt-in only. If you choose to include them, they are handled as limited, non-diagnostic context: clearly labelled, separated from everyday actions, and never framed as a standalone fear-led module.

What raw DNA files do you accept?

23andMe, AncestryDNA, MyHeritage, Living DNA, and other raw DNA files we can validate during the fit check. We're adding Nebula and Dante Whole-Genome support in Q3 2026. If you've lost your file, use the raw DNA download guide to find the official steps for your provider.

What if I have not taken a DNA test yet?

Choose a consumer DNA provider that lets you download your raw data after results are ready. We have tested several supported providers and confirmed highly comparable Spoke report outputs after our format, coverage, and quality checks. Provider marker coverage still varies, so the free fit check comes first.

How long does a report take?

Your Genome Action Plan is usually ready within 4 business days. We check the uploaded DNA file, run trait-specific genome analyses, prioritize the most useful findings, prepare your practical next steps, and review the report before delivery. If a file needs review by our team, we will tell you before taking payment or before analysis continues.

Can I share my report with my doctor?

Yes, if that is useful for you. The main report is written for you first: clear priorities, evidence labels, and practical next steps you can act on or track. When a finding is worth discussing, we include a concise clinical summary you can print, save, or attach to your patient portal.

What happens to my DNA file after the report?

Stored encrypted, used only to generate your report and any updates you request, never sold, never shared with insurers. One click in the portal deletes everything — file, derived data, and report. Receipts of deletion are emailed to you.

Is this a diagnosis?

No. Spoke reports are educational, designed to inform discussion with your doctor. Any clinical decision — medication, screening, surgery — requires confirmation through measured tests and a qualified healthcare professional. We say so on every page.

Availability updates

Join the first-release review list.

The first release is capped at 50 customers. Join the list and we will confirm whether your file is ready for checkout, needs a team review first, or should wait for a later release. No DNA file is needed at this stage.

No raw DNA upload here 50 first-release places Human follow-up from Spoke DNA
See the sample report →

Your details go to the Spoke DNA team. We will not ask for a DNA file through this form. Confirmation emails explain whether you can continue now, need file review first, or should wait for a later release.